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Buffalo Bills at New Orleans Saints Betting Preview

After filling up on Thanksgiving dinner, settle in for a matchup of second-place teams Thursday night as the Buffalo Bills (6-4, second in the AFC East) take on the New Orleans Saints (5-5, second in the NFC South). The Saints will host this one at the Caesars Superdome, with kickoff scheduled for 8:20 pm ET.

The Bills have been on a bit of a slide lately, losing two of their last three. Last week, they lost to the Colts at home 41-15. In the loss, Josh Allen threw for 209 yards and two touchdowns, but he also had two costly interceptions.

The Saints have also struggled as they come in, having lost three games in a row. Last week, they lost on the road 40-29 to the Philadelphia Eagles. Trevor Siemian threw for 214 yards and three scores in the loss, but he also had two interceptions. Siemian added a rushing touchdown as well.

The Bills are the favorites in this one despite playing on the road. They are -245 to win while the Saints’ moneyline sits at +200. The spread features New Orleans +6 (-110), and the over/under for total points is 45 (-110).

More Odds

Despite currently sitting in second, the Bills are the favorites to win the AFC East at -165. The Saints are +950 to win the NFC South.

In terms of the Super Bowl, the Bills are tied for the fourth-best odds of winning it all at +900. New Orleans is +7500 to win Super Bowl LVI.

By The Numbers

On the season, Buffalo has the second-best offense in the NFL, averaging 29.5 points per game. In their last three, though, they have averaged just 22 points. For the Saints, they rank 14th, averaging 25.1 points per game.

Defensively, it is again the Bills that hold the advantage. They are second overall in scoring defense, allowing opponents just 17.6 points per game. The Saints rank 10th allowing 21.8 points per game (27 at home).

Bills Looking For Consistency

The Buffalo Bills still believe they can be Super Bowl contenders this season, but if they are going to do that, they need more consistency. To date, they have played well against teams that are weak but are just 1-3 against opponents with winning records.

Still, the Bills will look for a big game out of Josh Allen and the offense in primetime, where Buffalo is 5-1 in their last six games.

For Allen, this season, he has thrown for 2,811 yards, 21 touchdowns, and eight interceptions. He also has rushed for 340 yards and another three scores.

Allen’s leading receiver to date has been Stefon Diggs. In 10 games, Diggs has 60 receptions for 773 yards and six touchdowns.

Saints Trying To Break Losing Streak

After three straight losses, the Saints sit two games back of the Buccaneers for the division lead. To try to make up ground, though, they are going to have to play better at the Superdome, where they are just 2-2 to this point.

With Jameis Winston out for the season, Trevor Siemian has been getting the start under center. In four games, he has thrown for 920 yards, eight touchdowns, and two interceptions.

Unfortunately, it appears that one of the Saints’ biggest weapons may miss another game as Alvin Kamara has been ruled out. That will likely mean Mark Ingram will get most of the work out of the backfield, although he is also listed as questionable due to a knee injury.

Through the air, Deonte Harris has been the most productive receiver for the Saints. He has 26 receptions for 418 yards and two scores.

Take Buffalo To Win And Cover

The biggest factor that jumps out in this one is how well Buffalo usually plays after a loss. In their last four losses, they have been 3-0-1 against the spread in their following games.

While Buffalo still has some kinks to work out, this one could turn into a shootout, and if that is the case, there is a lot more trust in Josh Allen to persevere than Trevor Siemian.

Take Buffalo to both win and cover the six points.

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