Sports Betting Picks

Buffalo Bills vs. San Francisco 49ers Betting Preview

Monday Night Football features a battle of AFC East versus NFC West as the Buffalo Bills (8-3) take on the San Francisco 49ers (5-6). Despite it being a “home” game for the 49ers, the game will be played at State Farm Stadium in Arizona due to COVID-19 restrictions in California. Kickoff is scheduled for 8:15 pm ET.

The Buffalo Bills have been playing some good football as of late. In fact, they are an Arizona Cardinals’ desperation hail Mary from being on a five-game winning streak. Despite the 32-30 disappointing loss two weeks ago, the Bills bounced back by beating the Chargers 27-17 last week. They will look to keep it rolling and fend off the second-place Miami Dolphins in their division.

The 49ers play in arguably the best division in all of football, and while they are currently in the last place in the division, they are still 5-6. Technically, they are still alive in the playoff hunt, but it would be a significant uphill climb to get there. That is nothing new to San Francisco, though, as they have been battling uphill against their own injuries all season long. Still, they will look to get to .500 with a victory over Buffalo Monday.

The San Francisco 49ers are the favorite in this one as their moneyline sits at -116. The Bills come in -102 to win. The spread features the Bills at +1.5 while the over/under for total points is 46.5.

By The Numbers

Offensively, the Buffalo Bills hold the advantage when it comes to points per game. They currently rank 10th in the NFL in scoring at 27.2 points per game. The 49ers fall to 20th overall averaging 23.7 points per game.

On the defensive side, it is the 49ers who hold the edge. They currently rank 11th overall in points allowed per game at 23.1. The Bills rank 18th, allowing 25.6 points per game.

Bills Look For Win Despite Being Road Underdog

The Buffalo Bills have played well this season as they currently lead the AFC East. Despite their success thus far, they come into this one as a slight underdog and will look to get the big road victory.

Leading the way for the Bills is quarterback Josh Allen. Last week, Allen struggled a bit, throwing for just 157 yards, 1 touchdown, and 1 interception, but he has been solid overall this year.

On the season, he has thrown for 3,028 yards, 22 touchdowns, and 8 interceptions. His leading receiver thus far has been Stefon Diggs, who has 80 receptions for 945 yards and 4 touchdowns. 

Defensively, the stat leaders include Jordan Poyer (71 tackles), A.J. Klein (5 sacks), and Jordan Poyer and Tre’Davious White with 2 interceptions apiece.

49ers Look For First Win In Their New Home

Due to COVID-19 restrictions in Santa Clara County, the 49ers had to find a new home for their next couple of games, and the Arizona Cardinals were accommodating to open their doors to San Francisco. Now, the 49ers will look for a “home” victory in their home away from home.

Under center for the 49ers is Nick Mullens. Since taking over for Jimmy Garoppolo, Mullens has thrown for 1,642 yards, 8 touchdowns, and 6 interceptions this season.

Last week, the 49ers welcomed back star wide receiver Deebo Samuel, and he didn’t disappoint. In the win over the Rams, he had 11 receptions for 133 yards. He will undoubtedly be a thorn in the Bills’ side and a comfort for quarterback Nick Mullens.

On the ground, Raheem Mostert leads the way. He also returned from injury last week and went for 16 carries for 43 yards and a touchdown.  

Defensively, the 49ers are led by Fred Warner (52 tackles and 2 interceptions), Kerry Hyder (7.5 sacks), and Jamar Taylor (2 interceptions).

Taking The Bills To Win

This should be a really fun matchup. Despite playing poorly last week, Josh Allen and the offense has been impressive for the Bills. Despite injuries, the 49ers continue to play strong defense. On Monday, one side will have to bend.

For my money, I am taking the Bills to be the ones to come out on top. As solid as San Francisco’s defense can be, injuries have just crippled their team as a whole, and I think the Bills will be able to come out on top on both sides of the ball. Especially given that they are being spotted 1.5 points, the Bills seem like the right play here.

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