Denver Broncos vs. Los Angeles Chargers Prediction – Week 6 NFL

The Denver Broncos (3-2) will face off against the Los Angeles Chargers (2-2) at Empower Field at Mile High this Sunday. The Broncos are riding high after snapping their eight-game losing streak to the Raiders last week, while the Chargers are looking to reset after a bye week and back-to-back losses.
Can Denver Continue Its Defensive Dominance?
The Broncos are on a roll with a three-game win streak, largely thanks to their stingy defense. Denver ranks second in the NFL in scoring defense, allowing just 11.8 points per game since their Week 1 loss to Seattle. Quarterback Bo Nix has settled into his role with the team, throwing 78 consecutive passes without an interception over the last three games. Head coach Sean Payton has emphasized a run-first identity, and the Broncos have rushed for over 100 yards in each of their last three wins.
The Broncos defense, led by cornerback Patrick Surtain II, has been a game-changer. Surtain, who was named NFL Defensive Player of the Week after last week’s win, continues to be one of the top corners in the league. Denver’s defense will look to shut down Justin Herbert and the Chargers’ offense, which has struggled in recent weeks.
Chargers Aim to Bounce Back After Bye Week
The Los Angeles Chargers are coming off a much-needed bye week after two straight losses. Injuries have plagued the Chargers, with quarterback Justin Herbert nursing a high ankle sprain that has hampered the offense. Head coach Jim Harbaugh is focused on cleaning up penalties and missed assignments to get the Chargers back on track.
Herbert, who has only thrown for 144.5 yards per game over the last two weeks, will need to step up if the Chargers want to avoid falling below .500. The return of star outside linebacker Joey Bosa (hip) is still in question, which could impact the Chargers’ ability to pressure Nix and slow down Denver’s rushing attack.
Prediction: Broncos to Cover in Defensive Battle
Both teams bring strong defenses into this matchup, making points hard to come by. Denver’s defense has been dominant, and with their offense finding rhythm under Bo Nix, we expect the Broncos to secure a fourth straight win. Our projected final score is 21-17 in favor of Denver, so we recommend taking the Broncos to cover the spread.
With the over/under line set at 42.5 points, our projection of 38 total points suggests taking the under is the best play for this game.