Kansas City Chiefs vs. Buffalo Bills Preview – November 17

The Kansas City Chiefs (9-0) and Buffalo Bills (8-2) meet on Sunday in a highly anticipated Week 11 matchup. Kickoff is set for 4:25 PM ET at Highmark Stadium. Both teams are among the NFL’s best, making this a potential playoff preview with major implications.
Kansas City Chiefs
Kansas City remains undefeated, chasing history as the first team to complete a 17-game regular season without a loss. Patrick Mahomes leads the Chiefs with 260.8 passing yards per game and a league-leading third-down conversion rate (52%). While his 12 touchdowns and four interceptions are modest, Mahomes’ playmaking ability has been critical in eight come-from-behind wins this season.
Defensively, the Chiefs are one of the league’s best, giving up just 17.9 points per game (5th) and 289.9 total yards (4th). Chris Jones anchors the defensive line, helping the team excel against both the pass and the run. With minimal injury concerns, Kansas City enters the game at near full strength, aiming to maintain their perfect record.
Buffalo Bills
The Bills have won five straight games and look to be the toughest test for the Chiefs this season. Josh Allen leads an offense averaging 29 points per game (3rd in the NFL), and his 17 touchdown passes highlight his ability to find the end zone. However, recent turnovers—four interceptions in the last three games—could be a concern against Kansas City’s opportunistic defense.
Buffalo’s defense is one of the league’s most opportunistic, ranking second in takeaways (19) and boasting a league-best +13 turnover margin. The unit allows 19.3 points per game, with Ed Oliver and Taron Johnson leading the way. Injuries, however, could hinder their depth, as players like Keon Coleman and Dalton Kincaid are questionable, and Matt Milano remains sidelined.
Prediction
- Score Prediction: Bills 27, Chiefs 24
- Key Factor: Buffalo’s ability to force turnovers and capitalize on red-zone opportunities will be the difference.
- Why Buffalo Wins: The Bills’ defense limits Mahomes’ big-play ability, while Allen delivers enough key moments to seal a narrow win.
This game is poised to be a thriller, featuring two of the NFL’s elite teams and top quarterbacks. Expect a back-and-forth battle that could set the tone for the rest of the season.