Sports Betting Picks

Baltimore Orioles vs Cleveland Guardians – MLB Preview – April 16, 2025

The Cleveland Guardians take on the Baltimore Orioles on Wednesday night at Oriole Park at Camden Yards. First pitch is set for 6:35PM ET. Cleveland won the first game of the series 6-3, improving to 9-7 on the season. Baltimore has fallen to 6-10 and has lost five of its last seven games.

Tuesday’s win was the sixth in seven games for Cleveland. They have outscored their opponents 39-23 during that stretch. Baltimore, on the other hand, has scored more than three runs in just one of its last seven games. The teams met ten times last season and split the series 5-5.

BAL Preview – Trying to Find Rhythm at the Plate

The Orioles are hitting .285 as a team, which is strong, but they are not converting that into runs. They are averaging 4.31 runs per game, but they have been held to three runs or fewer in five of their last seven. Their on-base percentage sits at .347, but they are striking out nearly seven times per game.

Dean Kremer has struggled on the mound, with a 1-2 record and 8.16 ERA through three starts. He gave up six runs in less than five innings in his last outing against Arizona. His WHIP sits at 1.54 and opponents are hitting .317 off him, which puts pressure on the bullpen early.

Adley Rutschman, Gunnar Henderson, and Ryan Mountcastle are the key bats in the middle of the lineup. Jackson Holliday is expected back in the starting nine, and manager Brandon Hyde is hoping for better results. The bullpen has been solid, especially Seranthony Dominguez and Yennier Cano, who have yet to allow an earned run.

CLE Preview – Offense Staying Aggressive

Cleveland has played well on the road lately, winning four of its last five away games. The Guardians are averaging 4.06 runs per game, and their offense has come through with key hits. In the first game of the series, they had 11 hits and just four strikeouts, showing good plate discipline.

Gavin Williams gets the start and is 1-0 with a 3.46 ERA in 2025. He threw five strong innings against the White Sox last week, striking out seven. Williams had trouble in his only previous game against the Orioles, but he enters this start with momentum after two wins in his last three starts.

Jose Ramirez and Steven Kwan continue to lead the offense. Kwan sets the table at the top with good contact and speed, while Ramirez provides the power in the middle. Bo Naylor and Carlos Santana add depth, and the bullpen has been strong with Paul Sewald and Cade Smith posting ERAs under 3.00. Cleveland’s relievers rank top-10 in ERA across the league.

Betting Prediction

The Guardians are underdogs at +115, while the Orioles are slight favorites at -124. The total is set at 8.0. Cleveland is in better form and has the more reliable pitcher in this matchup. The Guardians also have the edge in bullpen performance and team defense.

Cleveland is 8-7 to the under this year, and their pitching has kept games close. Baltimore’s bats have not produced many big innings, especially against stronger pitching. The Guardians should control this one behind Williams and their bullpen, with a predicted score of 5-3 Cleveland.

Pick: Cleveland Guardians +115

 

 

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