Indianapolis Colts vs Washington Commanders – NFL Preview – Week 4 – Oct 4, 2026

Ryan KnuppelSeptember 30, 2026

2 minutes read

The Indianapolis Colts will meet the Washington Commanders at Tottenham Hotspur Stadium in London on Sunday, October 4, 2026. The game kicks off at 9:30 AM on NFL Network. The Colts are 3.5-point favorites, with a moneyline of -195, while the Commanders stand at +161. The total over/under for the game is set at 47 points.

Both teams have 1-2 records this season, adding intrigue for bettors looking at early trends. The Colts have not won on the road yet, while the Commanders are undefeated at home. Bettors might look at the Colts’ favored spread or consider the Commanders’ home success when making their picks.

Indianapolis Colts: Season Snapshot

Daniel Jones leads the Indianapolis Colts as the starting quarterback. This season, he averages 233.4 passing yards and has thrown 1.7 touchdowns per game. Jonathan Taylor, the primary running back, supports Jones with an average of 89.7 rushing yards and nearly a touchdown each game.

The Colts’ offense depends on a balance between passing and rushing. Josh Downs and Keenan Allen are key wide receivers, with Downs projected for 61.2 receiving yards. Tight end Tyler Warren also contributes with 46.4 receiving yards per game.

On defense, the Colts have shown vulnerability, ranking 32nd in opponent offensive yards. DeForest Buckner and Grover Stewart are critical in the defensive line, while Sauce Gardner strengthens the secondary. The team will aim to improve its defensive performance to keep the opposing offense in check.

Washington Commanders: Season Snapshot

The Washington Commanders are preparing for their next game with Marcus Mariota expected to lead as the starting quarterback. Mariota has passed for 215.6 yards per game, contributing 1.4 touchdowns on average. On the injury front, Jayden Daniels is doubtful with an elbow issue, and this might solidify Mariota’s role even more. The Commanders have been alternating between their quarterbacks this season, but Mariota’s recent performance against Seattle could keep him in the spotlight.

In the backfield, Jacory Croskey-Merritt and Rachaad White are handling the rushing duties. Croskey-Merritt is averaging 53 rushing yards per game, while White adds versatility with 28.3 rushing yards and notable receptions. The Commanders’ running game is key to their offensive plan, especially with their passing unit ranking 25th in the league. Their rushing yards per game, however, sit at a solid 8th place.

On defense, the Commanders face challenges, allowing 362.3 yards per game, ranking 27th. Despite these struggles, the defensive line sees contributions from players like Kain Medrano and Sonny Styles. Medrano’s interception against the Seahawks last week was a crucial defensive play. With a focus on reducing opponent passing yards, the Commanders need their defense to step up against the Colts’ passing attack.

Betting Prediction

The Colts have struggled on defense this season. They rank last in opponent yards allowed per game and 24th in opponent scoring. This could lead to a high-scoring game, as both teams are in the bottom half for defensive rankings.

On the other hand, the Commanders also have defensive issues. They are near the bottom in opponent yards per game and scoring. Both teams have shown they can put up points, with the Commanders scoring 25 points per game and the Colts scoring 24.

Considering both teams’ defensive struggles and offensive capabilities, betting on the total going over seems like a smart move. The total is set at 47, which these teams can surpass given their scoring averages and defensive weaknesses.