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Seattle Seahawks vs Arizona Cardinals – NFL Preview – Week 2 – Sep 20, 2026

The Seattle Seahawks will visit the Arizona Cardinals on Sunday, September 20, 2026. The game will be held at State Farm Stadium in Glendale, AZ, and kick off at 4:25 PM on FOX. The consensus lines show the Seahawks favored by 4.5 points, with a moneyline of -209. The Cardinals have a moneyline of +174. The total points are set at 41.

Both teams enter Week 2 with a 1-0 record. Seattle’s offense may influence the game, with Brian Fleury as the offensive coordinator. Arizona, with Nathaniel Hackett as their offensive coordinator, will aim to keep pace. Bettors might look at the point spread and over/under as key angles in this game.

Seattle Seahawks: Season Snapshot

The Seattle Seahawks will rely on Drew Lock as the starting quarterback this week. He is projected to throw for over 170 yards with one touchdown. In the backfield, Jadarian Price leads the rushing attack, aiming to build on his 52 rushing yards from last game.

The wide receiver group will be led by Jaxon Smith-Njigba. He had an impressive 122 yards and a touchdown in the first game. Rashid Shaheed and Cooper Kupp are also expected to contribute in the passing game, providing additional targets for Lock.

Defensively, the Seahawks are strong, allowing only 10 points in their last game. Josh Jobe and Nehemiah Pritchett each secured an interception, highlighting the secondary’s performance. The defense will look to maintain pressure and create turnovers against the opposing offense.

Arizona Cardinals: Season Snapshot

The Arizona Cardinals are off to a solid start this season. Jacoby Brissett leads the team as the starting quarterback, with 229.4 projected passing yards for the upcoming game. He is supported by a mix of young talent and seasoned players in skill positions, such as Trey McBride at tight end and Marvin Harrison Jr. at wide receiver.

The Cardinals’ offense aims to balance both passing and running plays. Jeremiyah Love and Tyler Allgeier share duties in the backfield, with Love expected to gain 46.8 rushing yards in the next game. This combination of passing and rushing has helped the team rank 8th in offensive yards so far this season.

On defense, the Cardinals focus on limiting the opponent’s offensive gains. They rank 9th in opponent yards allowed, with a particular strength in stopping the run. Budda Baker and Andrew Wingard anchor the secondary, aiming to keep the opposing team’s passing game in check.

Betting Prediction

The Seattle Seahawks and Arizona Cardinals are set for an interesting game, with the total set at 41.0 points. Looking at the stats, both teams have strong defenses. The Seahawks allow only 10 points per game, ranking 2nd in the league. The Cardinals also have a solid defense, giving up just 14 points per game, ranking 4th.

Both offenses have been less impressive in the 2026 season. The Seahawks score 13 points per game, while the Cardinals average 26 points. With both teams’ defenses ranked in the top 5, it is likely that this game will be low-scoring.

The combination of strong defenses and the Seahawks’ offensive struggles suggests that taking the under is the best betting option. The numbers point to a game where points are hard to come by, making the under 41.0 a solid choice.

  • Pick: Total Under 41.0 (-110)

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